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News

Xpose 4 release 3 available 2008-10-24 10:31 - Xpose
A minor fix. In the previous release, in compute.cwres(), a debugging flag had been left in the file resulting in R going into debugging mode when this function was called. This has been fixed in this release.
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Xpose 4 release 2 available 2008-10-14 08:25 - Xpose
Xpose version 4.0.2 is now available. This is a maintenance release for xpose with improved functionality for xpose.VPC() and some minor bug fixes. To find out more please read the release notes on the download page.
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Xpose 4.0 release 1 now available! 2008-06-13 09:54 - Xpose
Our first non-preview release! This version of Xpose incorporates visual and numerical predictive check capabilities, in concert with Perl-speaks-NONMEM (http://psn.sf.net). For more information type, at the R command line:
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Update 1 to release 6 2007-05-31 20:27 - Xpose
A quick bug fix for titles of plots with multiple graphs. Now they can be specified to be anything the user desires. Just use the 'main' argument at the command line.
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Xpose 4 preview release 6 now available 2007-05-30 12:03 - Xpose
A new release of xpose is now available. This release changes the default way tables should be created so that xpose can calculate the CWRES, see the help page for 'compute.cwres' for more information. This release also updates the 'mirror' option, all plots in xpose can now handle the mirror option to create simulated comparison plots.
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Required Software

Xpose 4.0

R (2.2.0 or better)
Xpose >= 4.0 requires R, the open-source equivalent of S-PLUS, to run. R is available from its developers at no charge, and is licensed under the GNU GPL version 2. Only Microsoft Windows platforms are supported.

Hmisc (3.0 or better)
The Hmisc library for R contains many functions useful for data analysis, high-level graphics, utility operations, functions for computing sample size and power, importing datasets, imputing missing values, advanced table making, variable clustering, character string manipulation, conversion of S objects to LaTeX code, and recoding variables.

gam (0.96 or better)
The gam library for R contains functions for fitting and working with generalized additive models, as described in chapter 7 of Statistical Models in S (Chambers and Hastie (eds), 1991), and Generalized Additive Models (Hastie and Tibshirani, 1990).

akima (0.5-1 or better)
The akima library for R contains functions used in the gam library.

Xpose 3.104

Insightful S-PLUS (2000 or better)
Xpose 3.1 (as well as earlier versions) is a library written in S, as implemented in S-PLUS. Xpose versions <= 3.1 require S-PLUS as a host application, and will run under versions of the software for Microsoft Windows and UNIX/Linux.

Other Software

When complete, Xpose will be a fully-portable graphics library for NONMEM-related programming, meaning that it will be possible to embed it in other software.

Census
Census is a management application for NONMEM-based modelling projects. Census will adopt Xpose as its default visualization library - becoming its first de facto Windows frontend.
Perl-speaks-NONMEM (PsN)
PsN is a powerful, Perl-based environment for facilitating NONMEM model development. Xpose, Census and PsN will form a tightly-knit web of open-source, freely-available applications for NONMEM modelling and simulation.
R(D)COM Server
R, and by extension Xpose, can communicate with any other application in the Windows environment (Excel, for example). The R(D)COM server facilitates this process.